Role of indomethacin in polyhydramnios
نویسندگان
چکیده
Method: This was a prospective, longitudinal and analytical study conducted in Kathmandu University Hospital, Dhulikhel from 1st July 2011 to 1st of December 2012. There were 32 patients included in the study. Indomethacin was administered orally at the dose of 25 mg three times a day for 1 week. The patients were admitted for observation of clinical symptoms, fundal height, fetal status and amniotic fluid index measurement. After the delivery, baby was investigated for any abnormality of fetal circulation.
منابع مشابه
بررسی اثر درمانی ایندومتاسین در پلیهیدرآمنیوس شدید
Polyhydramnios is defined as excessive accumulation of amniotic fluid. It is associated with inceased incidence of abruptio placenta, preterm birth, cord prolopse and neonatal death (30%). So in this clinical trial, 12 pregnant women with significant polyhydramnios (AFI> 24 cm) and gestational age of 24-32 weeks, received oral Indomethacin at a dose of 100 mg/day for 8 days. AF volume decreased...
متن کاملIndomethacin in pregnancy: applications and safety.
Preterm labor (PTL) is a major cause of neonatal morbidity and mortality worldwide. Among the available tocolytics, indomethacin, a prostaglandin synthetase inhibitor, has been in use since the 1970s. Recent studies have suggested that prostaglandin synthetase inhibitors are superior to other tocolytics in delaying delivery for 48 hours and 7 days. However, increased neonatal complications incl...
متن کاملAntenatal Bartter Syndrome: A Review
Antenatal Bartter syndrome (ABS) is a rare autosomal recessive renal tubular disorder. The defective chloride transport in the loop of Henle leads to fetal polyuria resulting in severe hydramnios and premature delivery. Early onset, unexplained maternal polyhydramnios often challenges the treating obstetrician. Increasing polyhydramnios without apparent fetal or placental abnormalities should l...
متن کاملTransient Antenatal Bartter’s Syndrome: A Case Report
Antenatal Bartter's syndrome is a rare inherited disorder characterized by fetal polyhydramnios and polyuria that is usually detected between 24 and 30 weeks of gestation. However, a rare, severe, but transient form of antenatal Bartter's syndrome due to an x-linked melanoma-associated antigen D2 (MAGED2) mutation has recently been described. This transient type results in the earlier onset of ...
متن کاملNephrocalcinosis and Placental Findings in Neonatal Bartter Syndrome
Neonatal Bartter syndrome (NBS) is an inherited renal tubular disorder associated with hypokalemic alkalosis. Here we report a case of genetically diagnosed NBS. Polyhydramnios was noted at 26 weeks. A boy was born at 31 weeks and 1 day, weighed 1344 g, and had an Apgar score of 8/8. We initiated indomethacin (IND) at a dose of 0.2 mg/kg/d on day 31, and increased it to approximately 3 mg/kg/d....
متن کامل